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  1. Home
  2. NABP Certification
  3. NAPLEX Exam
  4. NABP.NAPLEX.v2023-10-31.q78 Dumps
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Question 71

What is the mEq/ml (Milliequivalents) of 50% Magnesium Sulfate? (Molecular weight of MgSO4 is
120.4g/mol.)

Correct Answer: B
Explanation
50gm/100ml * 1equiv/120.4gm * 1000meq/1equiv = 4.16meq/ml
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Question 72

Number of new cases per population at risk in a given time period is a definition of which of the following?

Correct Answer: A
Explanation
Incidence rate = New reported cases / summed person-years of observation (avg population during time interval). Prevalence = Cases in a population in a given time period / total population at that time Mortality rate
= deaths during specified time interval / population size at risk for death.
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Question 73

Concomitant use of warfarin and omeprazole is associated with increased INR and prothrombin time(PT).
What enzyme dose the omeprazole inhibits that is metabolized by warfarin?

Correct Answer: C
Explanation
Omeprazole is CYP2C19 inhibitor which can prolong the elimination of warfarin, particularly R-warfarin. R- warfarin is partially metabolized by CYP2C19. The combined use of omeprazole and warfarin has been associated with reports of increased INR and prothrombin time (PT).
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Question 74

LT is a 42-year-old white female with past medical history of epilepsy, gastroesophageal reflux disease and seasonal allergies. She weighs 86 kg, height 5'6" and allergic to Aspirin (rash) and Phenobarbital (difficulty breathing).
Her medications include Omeprazole 40mg daily, Phenytoin 200mg twice daily, Valproic acid 500mg four times daily, Loratadine 10mg daily. She comes to your community pharmacy to pick up prescription for Primidone 250mg twice daily.
Pertaining to Primidone what is the most appropriate action to take?

Correct Answer: B
Explanation
Primidone is an anticonvulsant drug that is structurally related to phenobarbital. Primidone is metabolized to phenobarbital and therefore shares its anticonvulsant and sedative properties. Primidone may be more effective than therapy with phenobarbital alone because primidone and both of its metabolites, phenobarbital and phenylethylmalonamide (PEMA), possess anticonvulsant activity.
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Question 75

Which of the following antidiabetic medication may cause cyanocobalamin deficiency?

Correct Answer: E
Metformin is associated with vitamin B12 deficiency because it affects the calcium dependent membrane uptake of it. All other drug classes are not associated with this.
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